C.V.
PhD (Genetics) Cambridge University 1968
MRC Junior Research Fellow, Cambridge University 1968 - 69
Postdoctoral fellow, University of Chicago 1969-71
Honorary Research Fellow, Liverpool University 1971-74
Temporary Lecturer, University of Sussex 1974-84
Visiting Scientist, NIEHS (NIH) North Carolina 1977-78
Research Associate, University of Chicago 1984-88
Assistant Professor, University of Chicago 1988-92
Professor, University of Chicago 1992-1997
NERC Senior Research Fellow, University of Edinburgh 1997-2002
Professorial Research Fellow, University of Edinburgh 1997-present
Fellow of the Royal Society 2005
Research groupings
Population genetics
Teaching
Molecular Evolution and Diversity, Evolutionary Genomics, Evolution of Sex and Mating Systems.
Research interests
Evolutionary and population genetics, particularly topics in the general area of the evolution of breeding systems. Linkage disequilibrium in the genome region containing the self-incompatibility alleles of the plant Arabidopsis lyrata, and estimation of this region’s rate of genetic recombination (to test whether it is unusually low, since it contains the two incompatibility loci, one encoding the pollen recognition protein and one the pistil receptor). DNA sequence diversity at other loci in populations of this species, aimed at comparing genomic patterns of evolution with its close relative A. thaliana. Molecular evolution of sex chromosomes, including studies of the evolution of Y-linked genes in the white campion, Silene latifolia.
Representative publications
Charlesworth, D,Wright, SI. (2001) Breeding systems and genome evolution. Current Opinion in Genetics & Development 11, 685-690.
Jesper S. Bechsgaard, Vincent Castric, Deborah Charlesworth, Xavier Vekemans, Mikkel H. Schierup. 2006. The transition to self-compatibility in Arabidopsis thaliana and evolution within S-haplotypes over 10 million years. Molecular Biology and Evolution 23: 1741-1750.
Asher D. Cutter, Scott E. Baird and Deborah Charlesworth. 2006 Patterns of nucleotide polymorphism and the decay of linkage disequilibrium in wild populations of Caenorhabditis remanei. Genetics 174: 901-913.
Bergero, R., A. Forrest, E. Kamau, and D. Charlesworth. 2007. Evolutionary strata on the X chromosomes of the dioecious plant Silene latifolia: evidence from new sex-linked genes. Genetics 175:1945-1954.
D. Charlesworth Balancing selection and its effects on sequences in nearby genome regions. PLoS Genetics 2: e64 DOI: 10.1371/journal.pgen.0020064.
|
